Alzheimer’s is a devastating brain disease, it is irreversible and progressively destroys thinking skills memory and later the ability to even perform the most simple daily tasks. For most people that suffer from Alzheimer’s they first see symptoms after the age of 60. Estimates show that as many as 2.4 to 5.1 million Americans suffer from this terrible disease. There has been some promising research with the organic compound resveratrol, which occurs naturally in red wine, may become a promising treatment in the future for Alzheimer’s.
Several recent epidemiological studies have shown that the moderate consumption of red wine is associated with lower incidents of dementia and Alzheimer’s disease. This is due to resveratrol, which is a naturally occurring organic compound found in some foods. It not only can be found in red wine but also some berries, grapes, and peanuts.
Resveratrol has been shown to neutralize the toxic effects of proteins linked to Alzheimer’s disease. The compound in itself is a antioxidant and is known for its many health benefits. Studies have shown that the disease is rare in places where the consumption of red wine is common and done on a regular basis.
One of these recent studies led by Professor Peter M. Tessier of the Rensselaer Polytechnic Institute with these important findings was published in the May edition of the “Journal of Biological Chemistry”. Research shows that resveratrol can hamper beta-amyloid, a protein found in those suffering in Alzheimer’s.
Researchers at the Litwin-Zucker Research Center for the Study of Alzheimer’s Disease & Memory disorders have conducted studies on the peptides, called amyloid-beta. These amyloid-beta peptides lead to the plagues in the brain that cause the disease Alzheimer’s. They found resveratrol was effective in encouraging the breakdown of this amyloid-beta peptide.
The full benefits of resveratrol against Alzheimer’s are still in the early stage of hypothesis and research. Nothing concrete has been proven yet, but these recent developments suggest that natural metabolites or potent synthetic analogues of Resveratrol have therapeutic potential treatment of the disease.
Further studies are needed to explore the potential role of resveratrol before we can proceed toward testing on human beings in clinical trials. These recent promising findings will help researchers explore treatments for Alzheimer’s disease in areas they may not have been considering before. These studies will not only show the full effect it has on Alzheimer’s but also other devastating amyloid related brain diseases like Huntington’s, Parkinson’s ad rare progressive neurodegenerative brain disorders.
Even though research and future development of resveratrol in treating Alzheimer’s is in the very early stages this research is promising. It gives hope to the millions of people worldwide who suffer from this devastating disease. These studies also give a positive outlook to the loved ones and families of those with Alzheimer’s. If you have a friend or family member that is dealing with this disease be sure to check here for support and resources from the Alzheimer’s Research Foundation. At their website you will be able to find information on caregiver resources, frequently asked questions, the most up to date research information and helpful hints on dealing with the daily burden of Alzheimer’s.
The Journal Of Biological Chemistry – www.jbc.org/content/early/2010/05/28/jbc.M110.133108.abstract
Rensselaer Polytechnic Institute – news.rpi.edu/update.do
Alzheimer’s Research Foundation – www.alzheimers-research.org/index.php
National Institute of Aging – www.nia.nih.gov/Alzheimers/AlzheimersInformation/GeneralInfo/
Webmd – www.webmd.com/alzheimers/news/20051104/compound-in-red-wine-may-fight-alzheimers